Multiple Sclerosis
The pathological condition in Multiple Sclerosis is nerve demyelination (loss of the protective covering around a nerve). Symptoms develop as nerve conduction slows and then fails completely. The typical attack is relatively sudden in onset, persists for 3 to 12 weeks, then clears. Classically, MS has a relapsing-remitting pattern. There are periods of remissions and exacerbations that occur at unpredictable intervals over a period of several years with initial episodes tending to resolve completely. It is the accumulated burden of multiple attacks that causes persistent symptoms.
Expectations:
While under treatment for an acute exacerbation or while under treatment with immune suppression: postpone.
Suspected MS but with no test results to support the diagnosis (no current evidence of disease and no treatment recommended):
| Condition | Rating |
| Within 2 years of the attack | Table 3 |
| 3-4 years of the attack | Table 2 |
| 4+ years after the attack | standard or better |
Definite MS, at least two clinical events and/or with test results to support the diagnosis, OR anyone for whom treatment has been recommended AND has minimal impairment, is ambulatory, independent, and stable:
Expectations:
| Condition | Rating |
| Within 2 years of the last attack | Table 7 |
| 3-5 years from last attack | Table 5 |
| 6-10 years from last attack | Table 3 |
| 10+ years from last attack | standard or better |
*NOTE: If the degree of severity is more than minimal: the rating will increase, and decline is likely on the most severe cases. Progressive neurological decline in less than a decade would be declined.
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Multiple Sclerosis eQuestionnaire